Breathing Issues. Promethazine/codeine might trigger gradual or shallow respiration, especially if you have got respiration issues from A further issue or consider other medicines that can sluggish your breathing.

When you are utilizing a liquid sort, use a medication-measuring device or spoon to diligently evaluate the prescribed dose. Do not utilize a household spoon since you may well not get the right dose. In the event your liquid type is usually a suspension, shake the bottle nicely in advance of Every single dose.

Allergic reactions to Ingredients. People who are allergic to any of the subsequent must not get promethazine/codeine.

If your doctor has directed you to make use of this medication, take into account that your health care provider has judged that the advantage to you personally is bigger than the chance of Uncomfortable side effects. Lots of individuals employing this medication don't have severe Unwanted side effects.

Lifestyle-threatening respiratory despair and Demise have transpired in youngsters who obtained codeine. Codeine is subject to variability in metabolism centered on CYP2D6 genotype (described down below), which may lead to an increased publicity to the active metabolite morphine. Primarily based on submit-advertising stories, children younger than twelve yrs outdated look like a lot more vulnerable to the respiratory depressant effects of codeine, especially if you will find hazard variables for respiratory depression.

Nursing mothers using codeine can also have larger morphine amounts within their breast milk When they are ultra-rapid metabolizers. These bigger levels of morphine in breast milk may produce lifetime-threatening or fatal Unwanted side effects in nursing toddlers. Instruct nursing mothers to Look ahead to signs of morphine toxicity inside their infants which includes elevated sleepiness (a lot more than typical), problem breastfeeding, breathing complications, or limpness.

Pets may be a common bring about for men and women’s allergic reactions. Cats, puppies, rabbits and also horses can all cause the sneezing and itching of check here an airborne allergy. Piriteze can provide reduction.

Human Data Published details from situation-Regulate and observational research on codeine use through pregnancy are inconsistent of their findings. Some reports of codeine publicity showed an elevated possibility of All round congenital malformations while some did not.

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When employed for an prolonged time, this medication may not perform in addition and may call for different dosing. Communicate with your physician if this medication stops working nicely.

The danger for significant respiration problems is bigger when You begin this medication, or if you take the wrong dose or take far more of the medication than prescribed. Getting this medication with alcohol or other medications that might cause drowsiness or breathing problems may well cause really severe website Unintended effects, which includes Dying. Also, other medicines can influence the removal of this products from your entire body, which may have an impact on how it really works.

We publish content that's researched, cited, edited and reviewed by accredited health care gurus. The data here we offer will not be meant to certainly be a substitute for Expert health-related tips, prognosis or procedure. It should not be employed in place of the recommendation of one's physician or other experienced Health care vendors.

This may not be a complete list of click here medicines that may interact with promethazine/codeine. Constantly Test with your Health care company.

No proof of tumorigenicity was observed in male and female mice at codeine dietary doses as much as 400 mg/kg/working day here (somewhere around comparable to 45 times the MRHD on the mg/m2 foundation).